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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3d7fcfe3a65065be0c4b16073c6ed1d220b4747a683d1d187f071f20367c24c0' 
  AND token = 'JOsDiRlU+XxOj5zGIPmyReAdgm104IEMkr2Pd8eN0/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}