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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '257580dabe68b1f5842e4f0f0b4f87429f2dc6f4c1909f37df07da5015d095e9' 
  AND token = 'JEIxKvSKyDxVr5fJP4edo++zN7DkJ3iNsLCfJJByYHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}