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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c5b65c94466a503711de40b075409a4e1bc3c3b7eaa5f58895006dd1de70a7fc' 
  AND token = 'ql9QQA9tO7DS4y4FBG8l+nx82rmppsDvIh4gJC0f4Fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}