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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5142184da40263f461bb9ec3624e074a8b37c05b456a82c2621508a48fc3825b' 
  AND token = 'MUsS15RKSgaZp/MCveJt1fQRnC2hUPQkc5Id1XtqnpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}