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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f726bab3865825aa0095a4e46c0a1655466c78a9692a802cfc0bb23cce1ebfaa' 
  AND token = 'K7BDBcyoZCLG/FkRl43B66fsL9eM+pj+1KM7TVrQWOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}