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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '56652d75968ab5d05720ff90d6b249371640fc1207d977f0a5d795bc914c2523' 
  AND token = '34W+uZbdpOtdhlQkuhM2VZBH0UG5Z1maO6qFF2aZ0sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}