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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49c35d7b6024474e4cda89f7df724c68c2f21edeb53eacfb94fe029e0695fe80' 
  AND token = '9a466bFDqydfXK7LeCKgTmW0pncLvoDwaCt+AEfed9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}