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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b014d018af65c2899bd2fe272d468e1e3924d1838b5e1af64bf03fd6d034a74' 
  AND token = 'fx366VFODnnC7AOq7vqEh3cXio5u+qePKEy5AaB3EZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}