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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01a9cf65b255a590b46d52d531f727e5023cc26ab68e4e5e89bc92b66afcceab' 
  AND token = 'k14MIfQWv0LJcI2tSSdRl6lw+Hiiz8LDdoXT5/ZXjp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}