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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '71b4d86d27e47644b602388897fc4e10ceb96bb821061a37b398b5d9e30d11f0' 
  AND token = '+NF+bcoVrOCiS+pfI4EHtPhPy9LyRu4wjaWqVnTPkSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}