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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cfb16c03774b3db73a1587c6ec4544915156c3decde4d392b40413b4b822fc8c' 
  AND token = 'XWEys1gw2PsGAlTJPinxmcLqomSwUUO5e3EHPpVqPPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}