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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d6996f6a550b58ed5ebb48048482bf677df049b90224ce43b4aea88b1308f72' 
  AND token = '2jhQDsblZYblaj5ixU/6N/DW6U5wg2wjLoas+xG/Ui4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}