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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22130401048a26854eb774b418376dcd51bdfd595804a774b99cacdd46ee6f5a' 
  AND token = 'CtfxK+rhTZI4zUuXagr1Kofeai46z1oQIBIAy17iPbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}