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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '61d0ca3c4b053675e3ea19a72fb0dd9daacc6d5fc7ba8033f1c65ccc858b8e4e' 
  AND token = 'azuHQ2MXY8syjuyNxiQq1zJsS7GsMKqC+PRSAKxtjgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}