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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3742d773aa0f32b345802c52c0a22a0750969283b9ef0865e2ba58efef4e8847' 
  AND token = 'cy6CarUiv0gIgrCUCfpuwB3G9HWY+R+TxWVWBeFTQpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}