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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78701f253415513921e41724e1530ebf913b41554f7eef6235a880bbf5999687' 
  AND token = 'iA/K38hd2+hU9mriaEcLVAXu58VxxaOTlItbjip7FLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}