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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80c023a4e01f07255d6cf1c81645a5a43005515aad6648b47a61951bb141b53b' 
  AND token = 'Q6aqPTVKd8kntviHscBxCN3zeo/IF25aC1Ta9TYINyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}