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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2df2090a7c7b6dc282605a2679a3a2209a81d3682e64024eea011efa2a64d789' 
  AND token = 'd5LZuPmys6qiAOM1MYzMRbyt2wi0t7m+0MaRIIFpwhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}