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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4fe72992853cd7439a39c4374d1884c3ef653d10f2978c4ca41f78308c07ac04' 
  AND token = 'yO2Rwr4egOAjJcDhJvKU3qn4KfkwaZpuT4Tt0d7bAGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}