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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '456a853bb5a644af0771a1fa3f0995d0c5350e58915c403c196b40d387b59507' 
  AND token = '6yrfik1HysAf5doXEnkFA3qZXC7qVrzSE+mRvtXpj+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}