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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f53bbacebf0d143549ae69b36539d1cbef74a31ef1880c287a5f2a062e9061f4' 
  AND token = 'dJC404AGHuQbGPYsgEqzuk8R27XLR9k7Z3S74y1h28o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}