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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e6daaf3b0e312725d615fbbc099d6ca26693583f5bf908c1fbbb2af6bcee644' 
  AND token = '+gdUBZXre801iq5BOKkbZRAXnUtXIL9sygOP8viwW4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}