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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '04451e587dc3082bf78b9edc87667a890a2c40f3deaaf7b9c3c2fa3731c9bd18' 
  AND token = '9RBpP3SEfmRgkvwpRjGdRrAlbQU4jBHTM6ZxPE5BsUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}