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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '377baeb6185e2ec7c272f76d68cf724d3d2f0c9963f744b76bdc71d9a0bab434' 
  AND token = 'eZQe5ez9Y5CucyQaQohwleRvB/rvL5C7NZfiSzXB4MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}