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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6b4811956616bbb747a03303b91b11255ccd0dd536d58f8e81acd5d28746dbee' 
  AND token = '04IODlPt+yE2DcVxk+sS4mJsApdHKM/qDbWvHmOdJZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}