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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e514445e02b988335ddda0ce15e15b19361e715bac64c0dc91132dfecdec03d' 
  AND token = 'xjMMysJ8bXr01g7A+AS0kPR6CiVjjuv5Y/a15rI3QFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}