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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '35c7d00f0343293060aa8b6db47f06eeecba0a9dfd37bbbe52dd75b4b4090562' 
  AND token = '/bFPcUWGoC0A8HhKx1W+h80CpwQi5ZFOdgPqhjbf7pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}