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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'caf745bcbd3bc10fd8eb6ae698e1e6ce173641dd39f70a64adc01420a4ff8555' 
  AND token = 'lfmO1VSl3fWW8WKzVhtGGWU/NMDLmxPZEN7mNfjaKVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}