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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a9d6c17d5b9c623c944036f59792b66e07797b36a1459cb11a376be94cd7180' 
  AND token = 'hhYrKJN87akK2QsHAP7VZguijjfnht5WBA6kJexc7XM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}