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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa1251facf799315a71ce34a189f1696ffd645ee1c3adb0e790e1aa9f25af7dd' 
  AND token = 'nEBhmlHx6xofFct4yZkYKveyhenwheMPmqlTbGUuM3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}