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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b045aed8ef2235060fdbcf29abfcdc1bcfe84431f0c3333b295f1e9efa2c643' 
  AND token = 'LVwFzZlLd4VkOl+a7pwwsaWO2ITSwTHWX6frKxAYiwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}