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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c22b5444af150c13ae78840e8bca143bfd9fa7c4deaee884630d1b3a7ad1054f' 
  AND token = 'R9LXAL8Y6vbAOHFLihweXgr4VzkRIXF8EU5hcc4eQbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}