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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd486f6dd5e483a5846b021560b9f45d0083e7ad0811338cc8f48981d88b2f488' 
  AND token = 'Wt8D1j6EPgK8QnTP++mP9/e3ALPV7O4QTGXFI9yGxuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}