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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2989cc14490825346680217c16fdc4bb07990bda86158d22d2c5e52ce86017e4' 
  AND token = 'u+8IY9t1GhvQPDpIDeCmPum1Lt2Toc9QEuPAzKHLB0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}