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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53185b335b1c60d66ba9e7d75e08239cf41e9f4e1d7199d9fa9f20c4454364c6' 
  AND token = 'sMmALPe/TQHLfezy8bZwimmHUHldIzRWEd8JJXtHEfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}