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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '80a6b1266db0c52fc33167a830be41cbc22a128a90546900f8103da33f2633e3' 
  AND token = 'ndudk2POMq05oQ/msr6xizDNj3B83WRN5N6kD79yS3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00190

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}