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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4550d0dbf41036ac79674029b16b1c04bd8db9d274ee4eb75bb5efb875fc7c74' 
  AND token = 'w2pVQiwQGno3HROO4P+nE+UFM3/QwQBLXYoo+/dDDnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}