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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '549f3497830fec757dd51a02f0214f495b6bfd47c3edd635da3ce799a5a3bc7e' 
  AND token = 'phMkLrHyd+YszOaWHvlz5vlv1/vfUX6Z7Tdkp83SB3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}