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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6fd4137cc6f245bffb024d047235d2dd3ac5f13261c8dd30d905c746d1ef0f65' 
  AND token = 'viM0Rd8KfvF69Lns3BWzWNyP6xKcRHOW7Ip4xLxNuPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}