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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2fa18e24570d3a76be9c330d311fa9ac66db2eba3caa450b60af6fc9ade70808' 
  AND token = 'lfdlSYXxZ4jS3i2udPF051vTu7U7mW5gLgNnlYjlgHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}