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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '26a6cc9f845fc83e48e43e6286440d5bbd420e0aa51eef01514ce72b4e26be57' 
  AND token = 'HDdEfW22V5jYIgYDWKHUCJJo9Yx7TuY7pJq9DDPru0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}