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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9cdd97a112859cc46192bef0fc2bd5e38f748c7173ac2bbbcc2c0b20ac44c5e4' 
  AND token = 'vPL4WG52GOT8o+vTxeFiElkOpabwknF4ZHgExKR0FoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}