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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a1e18f1f05b539a0aff43d8b7297adb812ad8c464c725fb8653a0a353196cdc0' 
  AND token = 'S/xlgg17FbU3Rss2BS5KsMe/syW3vgXqaA3ceru1uTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}