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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cf21db80bb33fdf896b3ae3eda2a3fd45ae8245d0bb0b20fe0399a2918fada87' 
  AND token = 'ZPJ9sjrO9nKelzYAAAsImJwFmfTdjdzE+ACYuzqLA2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}