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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22fa2803eea5a17a953ce87b4d84871ec4d031ad88de77470dc30124dd50dbb6' 
  AND token = 'zNiVftqhXHHN3+aYsNAf9b4CHuk3Ewfc26Sru+0DtIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}