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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e25e65d30b5ad5f4c13d9cefd791e126e5c0d73170d87d25f6deac142f64f024' 
  AND token = 'YKFKCHYIn29WUNdi2Zawoqx5opuVNOS6uGqA17xx/Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}