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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f79450e5c5b3343310d3fde89d18a137c0a943edfebee972daa53b9f6aeda144' 
  AND token = 'JwCcC0nYSDPZ7m2/5dsTRCnSbGah+uYLpOuqF0XEejo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}