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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7387140de37c12230a6fac9a8d2e0cd7a07f716bd63efeec084d894bf5fea80f' 
  AND token = 'f/BS7kJzfUW1fGcEU6TPZbVGR/GRT6oA3c3dc2dnmD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}