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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6ddf1d2da7569b103333a47b837f7da4549fb5f2e9d79d7abc7ce9df64329ec8' 
  AND token = 'S3MFJLbydhymL9k+1IFyODBQrg56tQHOwThZUsyD9Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}