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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd1370cca6e828073f29dc901d969962f7a4ff8256248b66057035fc04f4e8270' 
  AND token = '7rvEm7BnLdsY7YvXtQ4OHrapi1+XX5GyPCm1FNpFFsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}